An R implementation of the INSPIRE algorithm is freely available (Academic Use Only) as a CRAN package: https://cran.r-project.org/web/packages/INSPIRE/index.html You can install INSPIRE package using the command install.packages('INSPIRE'). Below is an example of how to call INSPIRE in R after installing the package. mcnt = 90 #module size lambda = .1 #penalty parameter to induce sparsity # download two real gene expression datasets in the package data('two_example_datasets')# the rows represent samples and columns represent genes in those datasets # log-normalize, and standardize each dataset res = INSPIRE(list(scale(log(exmp_dataset1)), scale(log(exmp_dataset2))), mcnt, lambda) |